产品货号：
Z11781
中文名称：
Bcl-X/BCL2L1抗体
英文名称：
Anti-Bcl-X/BCL2L1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Bcl-X/BCL2L1 Antibody |
| 指标别名 | Apoptosis regulator Bcl X;BCL2L1;Bcl-XL |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC-F,ICC,FCM |
| 基因名称 | BCL2L1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Bcl-X (75-105aa LDAREVIPMAAVKQALREAGDEFELRYRRAF),identical to the related mouse and rat sequences. |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Bcl-2-like protein 1,also known as Bcl-X,is a protein that in humans is encoded by the BCL2L1 gene.The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane,and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential,and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria,both of which are the potent inducers of cell apoptosis.Alternative splicing results in multiple transcript variants encoding two different isoforms.The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator. |
| Uniprot ID | Q07817 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | BCL2-like 1 |
| 蛋白名全称 | Bcl-2-like protein 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Frozen Section) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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